N-Cinnamoylation of Antimalarial Classics: Quinacrine Analogues with Decreased Toxicity and Dual-Stage Activity

Plasmodium falciparum, the causative agent of the most lethal form of malaria, is becoming increasingly resistant to most available drugs. A convenient approach to combat parasite resistance is the development of analogues of classical antimalarial agents, appropriately modified in order to restore...

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Bibliographic Details
Main Author: Gomes, Ana (author)
Other Authors: Perez, Bianca (author), Albuquerque, Ines (author), Machado, Marta (author), Prudencio, Miguel (author), Nogueira, Fatima (author), Teixeira, Catia (author), Gomes, Paula (author)
Format: article
Language:eng
Published: 1000
Subjects:
RESISTANT PLASMODIUM-FALCIPARUM
LIVER-STAGE
CHLOROQUINE
MALARIA
MOLECULES
INFECTION
Online Access:http://hdl.handle.net/10773/20948
Country:Portugal
Oai:oai:ria.ua.pt:10773/20948

Internet

http://hdl.handle.net/10773/20948

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