Ibuprofen inhibits colitis-induced overexpression of tumor-related Rac1b

The serrated pathway to colorectal tumor formation involves oncogenic mutations in the BRAF gene which are sufficient for initiation of hyperplastic growth but not for tumor progression. The analysis of colorectal tumors revealed that overexpression of splice variant Rac1b occurs in around 80% of tu...

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Detalhes bibliográficos
Autor principal: Matos, Paulo (author)
Outros Autores: Kotelevets, Larissa (author), Gonçalves, Vânia (author), Henriques, Andreia (author), Zerbib, Philipe (author), Moyer, Mary Ann (author), Chastre, Eric (author), Jordan, Peter (author)
Formato: article
Idioma:eng
Publicado em: 2013
Assuntos:
Vias de Transdução de Sinal e Patologias Associadas
Rac1b
Cancro Colorectal
Doença Inflamatória do Intestino
NSAID
Ibuoprofen
Texto completo:http://hdl.handle.net/10400.18/1200
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/1200

Texto Completo

http://hdl.handle.net/10400.18/1200

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