Ibuprofen inhibits colitis-induced overexpression of tumor-related Rac1b

The serrated pathway to colorectal tumor formation involves oncogenic mutations in the BRAF gene which are sufficient for initiation of hyperplastic growth but not for tumor progression. The analysis of colorectal tumors revealed that overexpression of splice variant Rac1b occurs in around 80% of tu...

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Bibliographic Details
Main Author: Matos, Paulo (author)
Other Authors: Kotelevets, Larissa (author), Gonçalves, Vânia (author), Henriques, Andreia (author), Zerbib, Philipe (author), Moyer, Mary Ann (author), Chastre, Eric (author), Jordan, Peter (author)
Format: article
Language:eng
Published: 2013
Subjects:
Vias de Transdução de Sinal e Patologias Associadas
Rac1b
Cancro Colorectal
Doença Inflamatória do Intestino
NSAID
Ibuoprofen
Online Access:http://hdl.handle.net/10400.18/1200
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/1200

Internet

http://hdl.handle.net/10400.18/1200

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