Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance

Background: Continuing evolution of the Mycobacterium tuberculosis (Mtb) complex genomes associated with resistance to anti-tuberculosis drugs is threatening tuberculosis disease control efforts. Both multi- and extensively drug resistant Mtb (MDR and XDR, respectively) are increasing in prevalence,...

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Bibliographic Details
Main Author: Oppong, Yaa E. A. (author)
Other Authors: Phelan, Jody (author), Perdigao, Joao (author), Machado, Diana (author), Miranda, Anabela (author), Portugal, Isabel (author), Viveiros, Miguel (author), Clark, Taane G. (author), Hibberd, Martin L. (author)
Format: article
Language:eng
Published: 2021
Subjects:
Drug resistance
Evolution
Mutations
Mycobacterium tuberculosis
Tuberculosis
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Infectious Diseases
Microbiology
SDG 3 - Good Health and Well-being
Online Access:http://hdl.handle.net/10362/116707
Country:Portugal
Oai:oai:run.unl.pt:10362/116707

Internet

http://hdl.handle.net/10362/116707

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