Comparative effects of three 1,4-dihydropyridine derivatives [OSI-1210, OSI-1211 (etaftoron), and OSI-3802] on rat liver mitochondrial bioenergetics and on the physical properties of membrane lipid bilayers: Relevance to the length of the alkoxyl chain in positions 3 and 5 of the DHP ring

The 1,4-dihydropyridines OSI-1210, OSI-1211 (etaftoron), and OSI-3802 are compounds with similar chemical structure. They differ by the length of the alkoxyl chain in positions 3 and 5 of the dihydropyridine (DHP) ring and by their pharmacological action characteristics. However, as far as we know,...

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Detalhes bibliográficos
Autor principal: Fernandes, Maria A. S. (author)
Outros Autores: Pereira, Susana P. S. (author), Jurado, Amália S. (author), Custódio, José B. A. (author), Santos, Maria S. (author), Moreno, António J. M. (author), Duburs, Gunars (author), Vicente, Joaquim A. F. (author)
Formato: article
Idioma:eng
Publicado em: 2008
Assuntos:
1,4-Dihydropyridine derivatives
Liver mitochondria
Mitochondrial bioenergetics
Animals
Cell Membrane
Dihydropyridines
Dose-Response Relationship, Drug
Male
Mitochondria, Liver
Models, Biological
Molecular Structure
Rats
Rats, Wistar
Structure-Activity Relationship
Energy Metabolism
Lipid Bilayers
Texto completo:http://hdl.handle.net/10316/5293
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5293

Texto Completo

http://hdl.handle.net/10316/5293

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