Mitochondrial-dependent apoptosis in Huntington's disease human cybrids

We investigated the involvement of mitochondrial-dependent apoptosis in Huntington's disease (HD) vs. control (CTR) cybrids, obtained from the fusion of human platelets with mitochondrial DNA-depleted NT2 cells, and further exposed to 3-nitropropionic acid (3-NP) or staurosporine (STS). Untreat...

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Bibliographic Details
Main Author: Ferreira, IL (author)
Other Authors: Nascimento, MV (author), Ribeiro, MH (author), Almeida, S (author), Cardoso, SM (author), Grazina, M (author), Pratas, J (author), Santos, MJ (author), Januário, C (author), Oliveira, CR (author), Rego, AC (author)
Format: article
Language:eng
Published: 2010
Subjects:
Apoptose
Doença de Huntington
Mitocôndria
Online Access:http://hdl.handle.net/10400.4/721
Country:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/721

Internet

http://hdl.handle.net/10400.4/721

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