Shedding light on miRNA targeting through structure

In miRNAs, it is known that seed pairing is an important parameter for targeting, but there are still missing links on why it targets a certain mRNA and how the decision between degradation or translation repression is made. In our work, we use liquid state NMR spectroscopy, EMSA and UV melting expe...

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Detalhes bibliográficos
Autor principal: Silva, Luis Filipe Santos Pereira Fernandes da (author)
Formato: masterThesis
Idioma:eng
Publicado em: 2020
Assuntos:
Texto completo:http://hdl.handle.net/10362/29427
País:Portugal
Oai:oai:run.unl.pt:10362/29427