Production of mannosylglycerate in Saccharomyces cerevisiae by metabolic engineering and bioprocess optimization

BACKGROUND: Mannosylglycerate (MG) is one of the most widespread compatible solutes among marine microorganisms adapted to hot environments. This ionic solute holds excellent ability to protect proteins against thermal denaturation, hence a large number of biotechnological and clinical applications...

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Bibliographic Details
Main Author: Faria, Cristiana (author)
Other Authors: Borges, Nuno (author), Rocha, Isabel (author), Santos, Helena (author)
Format: article
Language:eng
Published: 2019
Subjects:
Chemostat cultivation
Compatible solute
GDP-mannose
Mannosylglycerate
Metabolic engineering
Yeast cell factory
Biotechnology
Bioengineering
Applied Microbiology and Biotechnology
SDG 14 - Life Below Water
Online Access:https://doi.org/10.1186/s12934-018-1023-7
Country:Portugal
Oai:oai:run.unl.pt:10362/68109

Internet

https://doi.org/10.1186/s12934-018-1023-7

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