Genetic basis of Alzheimer's dementia: role of mtDNA mutations

Alzheimer's disease (AD) is the most common neurodegenerative disorder associated to dementia in late adulthood. Amyloid precursor protein, presenilin 1 and presenilin 2 genes have been identified as causative genes for familial AD, whereas apolipoprotein E epsilon4 allele has been associated t...

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Detalhes bibliográficos
Autor principal: Grazina, M (author)
Outros Autores: Pratas, J (author), Silva, F (author), Oliveira, S (author), Santana, I (author), Oliveira, CR (author)
Formato: article
Idioma:eng
Publicado em: 2010
Assuntos:
Doença de Alzheimer
DNA Mitocondrial
Péptidos Beta-Amilóide
Texto completo:http://hdl.handle.net/10400.4/894
País:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/894

Texto Completo

http://hdl.handle.net/10400.4/894

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