Genetic basis of Alzheimer's dementia: role of mtDNA mutations

Alzheimer's disease (AD) is the most common neurodegenerative disorder associated to dementia in late adulthood. Amyloid precursor protein, presenilin 1 and presenilin 2 genes have been identified as causative genes for familial AD, whereas apolipoprotein E epsilon4 allele has been associated t...

Full description

Bibliographic Details
Main Author: Grazina, M (author)
Other Authors: Pratas, J (author), Silva, F (author), Oliveira, S (author), Santana, I (author), Oliveira, CR (author)
Format: article
Language:eng
Published: 2010
Subjects:
Doença de Alzheimer
DNA Mitocondrial
Péptidos Beta-Amilóide
Online Access:http://hdl.handle.net/10400.4/894
Country:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/894

Internet

http://hdl.handle.net/10400.4/894

Similar Items