Cellular hypomethylation is associated with impaired nitric oxide production by cultured human endothelial cells

Hyperhomocysteinemia (HHcy) is a risk factor for vascular disease, but the underlying mechanisms remain incompletely defined. Reduced bioavailability of nitric oxide (NO) is a principal manifestation of underlying endothelial dysfunction, which is an initial event in vascular disease. Inhibition of...

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Bibliographic Details
Main Author: Barroso, M. (author)
Other Authors: Rocha, M. S. (author), Esse, R. (author), Gonçalves, I. Jr (author), Gomes, Anita Q. (author), Teerlink, T. (author), Jakobs, C. (author), Blom, H. J. (author), Loscalzo, J. (author), Rivera, I. (author), de Almeida, I. T. (author), Castro, R. (author)
Format: article
Language:eng
Published: 2013
Subjects:
Neurobiology
Proteomics
Life sciences
Biochemical engineering
Analytical chemistry
Biochemistry
Online Access:http://hdl.handle.net/10400.21/2618
Country:Portugal
Oai:oai:repositorio.ipl.pt:10400.21/2618

Internet

http://hdl.handle.net/10400.21/2618

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