Mitochondrial function in Parkinson's disease cybrids containing an nt2 neuron-like nuclear background

Mitochondria likely play a role in Parkinson's disease (PD) neurodegeneration. We modelled PD by creating cytoplasmic hybrid (cybrid) cell lines in which endogenous mitochondrial DNA (mtDNA) from PD or control subject platelets was expressed within human teratocarcinoma (NT2) cells previously d...

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Bibliographic Details
Main Author: Esteves, AR (author)
Other Authors: Domingues, AF (author), Ferreira, IL (author), Januário, C (author), Swerdlow, RH (author), Oliveira, CR (author), Cardoso, SM (author)
Format: article
Language:eng
Published: 2008
Subjects:
Doença de Parkinson
Mitocôndria
Online Access:http://hdl.handle.net/10400.4/333
Country:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/333

Internet

http://hdl.handle.net/10400.4/333

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