Mitochondrial function in Parkinson's disease cybrids containing an nt2 neuron-like nuclear background

Mitochondria likely play a role in Parkinson's disease (PD) neurodegeneration. We modelled PD by creating cytoplasmic hybrid (cybrid) cell lines in which endogenous mitochondrial DNA (mtDNA) from PD or control subject platelets was expressed within human teratocarcinoma (NT2) cells previously d...

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Detalhes bibliográficos
Autor principal: Esteves, AR (author)
Outros Autores: Domingues, AF (author), Ferreira, IL (author), Januário, C (author), Swerdlow, RH (author), Oliveira, CR (author), Cardoso, SM (author)
Formato: article
Idioma:eng
Publicado em: 2008
Assuntos:
Doença de Parkinson
Mitocôndria
Texto completo:http://hdl.handle.net/10400.4/333
País:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/333

Texto Completo

http://hdl.handle.net/10400.4/333

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