Microglia response and in vivo therapeutic potential of methylprednisolone-loaded dendrimer nanoparticles in spinal cord injury

The control and manipulation of cells that trigger secondary mechanisms following spinal cord injury (SCI) is one of the fi rst opportunities to minimize its highly detrimental outcomes. Herein, the ability of surface-engineered carboxymethylchitosan/ polyamidoamine (CMCht/PAMAM) dendrimer nanoparti...

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Detalhes bibliográficos
Autor principal: Cerqueira, Susana R. (author)
Outros Autores: Oliveira, Joaquim M. (author), Silva, N. A. (author), Leite-Almeida, Hugo (author), Samy, S. M. (author), Almeida, A. (author), Mano, J. F. (author), Sousa, Nuno (author), Salgado, A. J. (author), Reis, R. L. (author)
Formato: article
Idioma:eng
Publicado em: 2013
Assuntos:
Dendrimer nanoparticles
Intracellular delivery
Methylprednisolone
Microglia
Spinal cord injury
Science & Technology
Texto completo:http://hdl.handle.net/1822/23603
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/23603

Texto Completo

http://hdl.handle.net/1822/23603

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