Subunits of the chaperonin CCT are associated with Tetrahymena microtubule structures and are involved in cilia biogenesis

The cytosolic chaperonin CCT is a heterooligomeric complex of about 900 kDa that mediates the folding of cytoskeletal proteins. We observed by indirect immunofluorescence that the Tetrahymena TpCCTalpha, TpCCTdelta, TpCCTepsilon, and TpCCTeta-subunits colocalize with tubulin in cilia, basal bodies,...

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Bibliographic Details
Main Author: Seixas, Cecília (author)
Other Authors: Casalou, Cristina (author), Melo, Luís Viseu (author), Nolasco, Sofia (author), Brogueira, Pedro (author), Soares, Helena (author)
Format: article
Language:eng
Published: 2014
Subjects:
Chaperonin-CCT
Tetrahymena
Microtubules
Cilia
Blotting, Western
Chaperonin containing TCP-1
Cycloheximide
Cytosol
Fluorescent antibody technique
Protein folding
Protein transport
Protozoan proteins
Online Access:http://hdl.handle.net/10400.21/3046
Country:Portugal
Oai:oai:repositorio.ipl.pt:10400.21/3046

Internet

http://hdl.handle.net/10400.21/3046

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