Determination of lamotrigine in human plasma and saliva using microextraction by packed sorbent and high performance liquid chromatography–diode array detection: An innovative bioanalytical tool for therapeutic drug monitoring

A ground-breaking high-performance liquid chromatography-diode array detection method based on microextraction by packed sorbent (MEPS) as sample preparation approach is described herein for determination of lamotrigine (LTG), a narrow therapeutic index drug, in human plasma and saliva. MEPS variabl...

Full description

Bibliographic Details
Main Author: Ventura, Sandra (author)
Other Authors: Rodrigues, Márcio (author), Pousinho, Sarah (author), Falcão, Amílcar (author), Alves, Gilberto (author)
Format: article
Language:eng
Published: 2016
Subjects:
Lamotrigine
Liquid chromatography
Microextraction by packed sorbent
Plasma and saliva
Therapeutic drug monitoring
Online Access:http://hdl.handle.net/10314/3100
Country:Portugal
Oai:oai:bdigital.ipg.pt:10314/3100

Internet

http://hdl.handle.net/10314/3100

Similar Items