Cytotoxic effects of metal complexes of biogenic polyamines. I. Platinum(II) spermidine compounds: prediction of their antitumour activity

Cytotoxicity and cell growth inhibition studies were performed for three distinct polynuclear platinum(II) complexes of spermidine, which showed to have significant cytotoxic and antiproliferative properties on the HeLa cancer cell line. The chemical environment of the metal centres in the drugs, as...

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Bibliographic Details
Main Author: Marques, M. P. M. (author)
Other Authors: Girão, T. (author), Lima, Maria C. Pedroso de (author), Gameiro, A. (author), Pereira, E. (author), Garcia, P. (author)
Format: article
Language:eng
Published: 2002
Subjects:
Platinum complex
Spermidine
HeLa cell
Cytotoxicity
Antitumor activity
Online Access:http://hdl.handle.net/10316/3882
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/3882

Internet

http://hdl.handle.net/10316/3882

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