Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse

Parkinson disease (PD) is a chronic and progressive neurological disease associated with a loss of dopaminergic neurons. In most cases the disease is sporadic but genetically inherited cases also exist. One of the major pathological features of PD is the presence of aggregates that localize in neuro...

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Bibliographic Details
Main Author: Perfeito, Rita (author)
Other Authors: Cunha-Oliveira, Teresa (author), Rego, Ana Cristina (author)
Format: article
Language:eng
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10316/20790
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/20790