Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism
Cholestasis results from hepatocyte dysfunction due to the accumulation of bile acids in the cell, many of which are known to be cytotoxic. Recent evidence implicates competitive antagonism of key cytotoxic responses as the mechanism by which certain therapeutic bile acids might afford cytoprotectio...
Main Author: | |
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Other Authors: | , |
Format: | article |
Language: | eng |
Published: |
2002
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Subjects: | |
Online Access: | http://hdl.handle.net/10316/5420 |
Country: | Portugal |
Oai: | oai:estudogeral.sib.uc.pt:10316/5420 |