Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism

Cholestasis results from hepatocyte dysfunction due to the accumulation of bile acids in the cell, many of which are known to be cytotoxic. Recent evidence implicates competitive antagonism of key cytotoxic responses as the mechanism by which certain therapeutic bile acids might afford cytoprotectio...

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Bibliographic Details
Main Author: Rolo, Anabela P. (author)
Other Authors: Palmeira, Carlos M. (author), Wallace, Kendall B. (author)
Format: article
Language:eng
Published: 2002
Subjects:
Online Access:http://hdl.handle.net/10316/5420
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5420