Antibodies aggravate the development of ischemic heart failure

Heart-specific antibodies have been widely associated with myocardial infarction (MI). However, it remains unclear whether autoantibodies mediate disease progression or are a byproduct of cardiac injury. To disambiguate the role of immunoglobulins in MI, we characterized the development of ischemic...

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Detalhes bibliográficos
Autor principal: Keppner, Lea (author)
Outros Autores: Heinrichs, Margarete (author), Rieckmann, Max (author), Jocelyne, Demengeot (author), Frantz, Stefan (author), Hofmann, Ulrich (author), Ramos, Gustavo (author)
Formato: article
Idioma:eng
Publicado em: 2020
Assuntos:
Agammaglobulinemia
Animals
Autoantibodies
Disease Models, Animal
Extracellular Matrix
Fibrosis
Heart Failure
Immunoglobulin M
Male
Mice, Inbred C57BL
Mice, Transgenic
Myocardial Infarction
Myocarditis
Myocardium
Receptors, IgG
Ventricular Function, Left
Ventricular Remodeling
Immunoglobulin Class Switching
Texto completo:http://hdl.handle.net/10400.7/948
País:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/948

Texto Completo

http://hdl.handle.net/10400.7/948

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