Molecular changes associated with the origin of centrosome amplification in human cancer

The centrosome plays a critical role in maintaining cellular homeostasis by actively participating in microtubule nucleation, cell division, polarity, signaling and migration. Abnormalities in centrosome structure or number, including centrosome amplification, are a hallmark of human cancer. Centros...

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Bibliographic Details
Main Author: Nunes, Leonor Ferreira dos Santos Pereira (author)
Format: masterThesis
Language:eng
Published: 2022
Subjects:
Centrosome
Centrosome amplification
Human cancer
Barrett’s esophagus
Subdistal appendages
Domínio/Área Científica::Engenharia e Tecnologia::Engenharia Médica
Online Access:http://hdl.handle.net/10362/89774
Country:Portugal
Oai:oai:run.unl.pt:10362/89774

Internet

http://hdl.handle.net/10362/89774

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