Genetic Variants of the MGAT5 Gene Are Functionally Implicated in the Modulation of T Cells Glycosylation and Plasma IgG Glycome Composition in Ulcerative Colitis

OBJECTIVES: The impact of genetic variants (single nucleotide polymorphisms [SNPs]) in the clinical heterogeneity of ulcerative colitis (UC) remains unclear. We showed that patients with UC exhibit a deficiency in MGAT5 glycogene transcription in intestinal T cells associated with a hyperimmune resp...

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Detalhes bibliográficos
Autor principal: Pereira, MS (author)
Outros Autores: Durães, C (author), Catarino, TA (author), Costa, JL (author), Cleynen, I (author), Novokmet, M (author), Krištic, J (author), Štambuk, J (author), Conceição-Neto, N (author), Machado, JC (author), Marcos-Pinto, R (author), Magro, F (author), Vermeire, S (author), Lauc, G (author), Lago, P (author), Pinho, S (author)
Formato: article
Idioma:eng
Publicado em: 2020
Texto completo:https://hdl.handle.net/10216/142536
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/142536

Texto Completo

https://hdl.handle.net/10216/142536

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