Can epigenetic and inflammatory biomarkers identify clinically aggressive prostate cancer?

Prostate cancer (PCa) is a highly prevalent malignancy and constitutes a major cause of cancer-related morbidity and mortality. It emerges through the acquisition of genetic and epigenetic alterations. Epigenetic modifications include DNA methylation, histone modifications and microRNA deregulation....

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Bibliographic Details
Main Author: Santos, Pedro Bargão (author)
Other Authors: Patel, Hitendra (author), Henrique, Rui (author), Félix, Ana (author)
Format: review
Language:eng
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/10362/94246
Country:Portugal
Oai:oai:run.unl.pt:10362/94246