CD44 glycoprotein in cancer: A molecular conundrum hampering clinical applications

CD44 is a heavily glycosylated membrane receptor playing a key role in cell adhesion, signal transduction and cytoskeleton remodelling. It is also one of the most studied glycoproteins in cancer, frequently explored for stem cell identification, and associated with chemoresistance and metastasis. Ho...

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Bibliographic Details
Main Author: Azevedo, R (author)
Other Authors: Gaiteiro, C (author), Peixoto, A (author), Relvas-Santos, M (author), Lima, L (author), Santos, L (author), Ferreira, JA (author)
Format: article
Language:eng
Published: 2018
Subjects:
Cancer biomarkers
CD44
CD44 isoforms
Glycosylation
Nomenclature
Online Access:https://hdl.handle.net/10216/126486
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/126486

Internet

https://hdl.handle.net/10216/126486

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