Evaluating cytotoxic and genotoxic effects of microcystin using Saccharomyces cerevisiæ as eukaryotic cell model

Microcystins (MC) are one of the most common hepatoxins, produced by cyanobacteria. These toxins are cyclic peptides that have a high affinity for the Serine / Threonine (PPs) protein phosphatases family, namely PP1 / PP2A, acting as their inhibitors. MCs also induce oxidative stress in cells throug...

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Bibliographic Details
Main Author: Barreiros, Sara (author)
Other Authors: Silva, Maria João (author), Valério, Elisabete (author)
Format: conferenceObject
Language:eng
Published: 2017
Subjects:
Saccharomyces cerevisiae
Microcystins
Cytotoxicity
Genotoxicity
MTT
Comet Assay
Real-Time Polymerase Chain Reaction
Genotoxicidade Ambiental
Online Access:http://hdl.handle.net/10400.18/4682
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/4682

Internet

http://hdl.handle.net/10400.18/4682

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