Innate IFN-γ-Producing Cells Developing in the Absence of IL-2 Receptor Common γ-Chain

IFN-γ is known to be predominantly produced by lymphoid cells such as certain subsets of T cells, NK cells, and other group 1 innate lymphoid cells. In this study, we used IFN-γ reporter mouse models to search for additional cells capable of secreting this cytokine. We identified a novel and rare po...

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Bibliographic Details
Main Author: Resende, M (author)
Other Authors: Cardoso, MS (author), Ribeiro, AR (author), Flórido, M (author), Borges, M (author), Castro, AG (author), Alves, NL (author), Cooper, AM (author), Appelberg, R (author)
Format: article
Language:eng
Published: 2017
Subjects:
Animals
Antibodies, Monoclonal/administration & dosage
DNA-Binding Proteins/deficiency
DNA-Binding Proteins/genetics
DNA-Binding Proteins/immunology
Granuloma/immunology
Granuloma/microbiology
Hematopoietic Stem Cells/immunology
Immunity, Innate
Immunocompromised Host/immunology
Interferon-gamma/biosynthesis
Interferon-gamma/genetics
Interferon-gamma/immunology
Interleukin Receptor Common gamma Subunit/deficiency
Interleukin Receptor Common gamma Subunit/genetics
Interleukin Receptor Common gamma Subunit/immunology
Killer Cells, Natural/immunology
Leukocyte Common Antigens/genetics
Leukocyte Common Antigens/immunology
Liver/cytology
Liver/immunology
Liver/microbiology
Macrophages/immunology
Mice
Mice, Inbred C57BL
Mycobacterium avium/growth & development
Mycobacterium avium/immunology
Nitric Oxide Synthase Type II/biosynthesis
Nitric Oxide Synthase Type II/genetics
Nitric Oxide Synthase Type II/immunology
Spleen/cytology
Spleen/immunology
Thy-1 Antigens/genetics
Thy-1 Antigens/immunology
Online Access:http://hdl.handle.net/10216/114501
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/114501

Internet

http://hdl.handle.net/10216/114501

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