Iron-citrate can induce cell senescent phenotype in human fibroblasts in vitro
After a number of replications, human diploid fibroblasts (HDFs) in culture lose the ability to divide, become insensitive to further proliferation and enter a state of replicative senescence (RS). Subcytotoxic doses of several stressful agents such as hydrogen peroxide, tertbutylhydroperoxide or et...
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Formato: | article |
Idioma: | eng |
Publicado em: |
2009
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Texto completo: | https://repositorio-aberto.up.pt/handle/10216/101664 |
País: | Portugal |
Oai: | oai:repositorio-aberto.up.pt:10216/101664 |