Evidence for nevirapine bioactivation in man: Searching for the first step in the mechanism of nevirapine toxicity.

Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor used against human immunodeficiency virus type-1 (HIV-1), mostly to prevent mother-to-child HIV-1 transmission in developing countries. Despite its clinical efficacy, NVP administration is associated with a variety of toxic respons...

Full description

Bibliographic Details
Main Author: Caixas, U (author)
Other Authors: Antunes, A (author), Marinho, A (author), Godinho, A (author), Grilo, N (author), Marques, M (author), Oliveira, M (author), Branco, T (author), Monteiro, E (author), Pereira, S (author)
Format: article
Language:eng
Published: 2012
Subjects:
Antiretrovirais
Infecção por HIV
Nevapirine
Toxicidade de medicamentos
HIV
Toxicity
Online Access:http://hdl.handle.net/10400.10/664
Country:Portugal
Oai:oai:repositorio.hff.min-saude.pt:10400.10/664

Internet

http://hdl.handle.net/10400.10/664

Similar Items