Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells

A major risk factor promoting tumor development is chronic inflammation and the use of nonsteroidal anti-inflammatory drugs (NSAID), including ibuprofen, can decrease the risk of developing various types of cancer, including colorectal cancer (CRC). Although the molecular mechanism behind the antitu...

Full description

Bibliographic Details
Main Author: Gonçalves, Vânia (author)
Other Authors: Henriques, Andreia F.A. (author), Matos, Paulo (author), Jordan, Peter (author)
Format: article
Language:eng
Published: 2021
Subjects:
Ibuprofen
RAC1B
Alternative Splicing
Colorectal Cancer Cells
Protein Kinase
Vias de Transdução de Sinal e Patologias Associadas
Cancro Colorectal
splicing Alternativo
Online Access:http://hdl.handle.net/10400.18/7498
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/7498

Internet

http://hdl.handle.net/10400.18/7498

Similar Items