Anticancer Activity of Phenolic Acids of Natural or Synthetic Origin:  A Structure−Activity Study

Several phenolic acids-caffeic and gallic acid derivatives-were synthesized and screened for their potential antiproliferative and cytotoxic properties, in different human cancer cell lines: mammary gland and cervix adenocarcinomas and lymphoblastic leukemia. The selected phenols were structurally r...

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Bibliographic Details
Main Author: Gomes, Catarina A. (author)
Other Authors: Cruz, Teresa Girão da (author), Andrade, José L. (author), Milhazes, Nuno (author), Borges, Fernanda (author), Marques, M. Paula M. (author)
Format: article
Language:eng
Published: 2003
Subjects:
Adenocarcinoma
Antineoplastic Agents
Breast Neoplasms
Caffeic Acids
Cell Division
Cell Line, Tumor
Cell Survival
Drug Screening Assays, Antitumor
Female
Gallic Acid
Humans
Leukemia, Lymphoid
Magnetic Resonance Spectroscopy
Models, Molecular
Molecular Conformation
Phenols
Spectrometry, Mass, Electrospray Ionization
Spectrophotometry, Ultraviolet
Spectroscopy, Fourier Transform Infrared
Structure-Activity Relationship
Uterine Cervical Neoplasms
Online Access:http://hdl.handle.net/10316/45155
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/45155

Internet

http://hdl.handle.net/10316/45155

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