Synthesis of organometallic ruthenium(II) complexes with strong activity against several human cancer cell lines

A new family of "RuCp" (Cp=η(5)-C(5)H(5)) derivatives with bidentate N,O and N,N'-heteroaromatic ligands revealed outstanding cytotoxic properties against several human cell lines namely, A2780, A2780CisR, HT29, MCF7, MDAMB231, and PC3. IC(50) values were much lower than those found f...

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Detalhes bibliográficos
Autor principal: Mendes, Paulo J. (author)
Formato: article
Idioma:eng
Publicado em: 2013
Assuntos:
Texto completo:http://hdl.handle.net/10174/7208
País:Portugal
Oai:oai:dspace.uevora.pt:10174/7208