Role of SOX2 on RasV12-mediated transformation

The SRY (sex-determining region Y) - box 2 (SOX2) is a master factor in the maintenance of pluripotency and stemness. The transcription factor SOX2 allows the cells to maintain the unique characteristics of the embryonic stem cells (ESCs), such as clonogenicity, pluripotency, self-renewal ability, a...

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Bibliographic Details
Main Author: Fernandes, Tânia Patrícia Dias (author)
Format: masterThesis
Language:eng
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10773/22010
Country:Portugal
Oai:oai:ria.ua.pt:10773/22010