Role of SOX2 on RasV12-mediated transformation

The SRY (sex-determining region Y) - box 2 (SOX2) is a master factor in the maintenance of pluripotency and stemness. The transcription factor SOX2 allows the cells to maintain the unique characteristics of the embryonic stem cells (ESCs), such as clonogenicity, pluripotency, self-renewal ability, a...

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Detalhes bibliográficos
Autor principal: Fernandes, Tânia Patrícia Dias (author)
Formato: masterThesis
Idioma:eng
Publicado em: 2017
Assuntos:
Texto completo:http://hdl.handle.net/10773/22010
País:Portugal
Oai:oai:ria.ua.pt:10773/22010