Behind the curtain: unveiling DIS3L2 role in NMD and human cancer

Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism that targets and degrades mRNAs carrying premature translation-termination codons (PTCs), preventing the production of truncated proteins potentially harmful for the cells. In addition to this, several studies have shown that NMD regulat...

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Bibliographic Details
Main Author: Costa, Paulo (author)
Other Authors: Saramago, Margarida (author), Viegas, Sandra (author), Arraiano, Cecília (author), Romão, Luísa (author)
Format: conferenceObject
Language:eng
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10400.18/5115
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/5115