Occurrence of Guillain-Barre syndrome during the initial symptomatic phase of COVID-19 disease: coincidence or consequence?

Viral infections are frequently present before the clinical manifestation of Guillain-Barre syndrome (GBS). Multiple studies on coronaviruses have shown that these viruses have neurotropic characteristics, and their molecular mimicry can induce inflammatory demyelinating neuropathy. Herein, we descr...

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Detalhes bibliográficos
Autor principal: Seixas, Rui (author)
Outros Autores: Campoamor, David (author), Lopes, João (author), Bernardo, Teresa (author), Nzwalo, Hipólito (author), Pascoalinho, Dulce (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
Texto completo:http://hdl.handle.net/10400.1/17374
País:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/17374
Descrição
Resumo:Viral infections are frequently present before the clinical manifestation of Guillain-Barre syndrome (GBS). Multiple studies on coronaviruses have shown that these viruses have neurotropic characteristics, and their molecular mimicry can induce inflammatory demyelinating neuropathy. Herein, we describe a case of a GBS in an 85-year-old patient infected with SARS-CoV-2, manifested with acute progressive symmetric ascending quadriparesis, urinary dysautonomia, and dysphagia, who responded well to treatment with intravenous human immunoglobulin.