Occurrence of Guillain-Barre syndrome during the initial symptomatic phase of COVID-19 disease: coincidence or consequence?

Viral infections are frequently present before the clinical manifestation of Guillain-Barre syndrome (GBS). Multiple studies on coronaviruses have shown that these viruses have neurotropic characteristics, and their molecular mimicry can induce inflammatory demyelinating neuropathy. Herein, we descr...

Full description

Bibliographic Details
Main Author: Seixas, Rui (author)
Other Authors: Campoamor, David (author), Lopes, João (author), Bernardo, Teresa (author), Nzwalo, Hipólito (author), Pascoalinho, Dulce (author)
Format: article
Language:eng
Published: 2021
Subjects:
Viral mimicry
Neurotropic virus
Viral infections
Covid-19
Guillain barre syndrome
Online Access:http://hdl.handle.net/10400.1/17374
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/17374
Description
Summary:Viral infections are frequently present before the clinical manifestation of Guillain-Barre syndrome (GBS). Multiple studies on coronaviruses have shown that these viruses have neurotropic characteristics, and their molecular mimicry can induce inflammatory demyelinating neuropathy. Herein, we describe a case of a GBS in an 85-year-old patient infected with SARS-CoV-2, manifested with acute progressive symmetric ascending quadriparesis, urinary dysautonomia, and dysphagia, who responded well to treatment with intravenous human immunoglobulin.

Similar Items