The interplay between mRNA translation and nonsense-mediated decay in transcripts with short open reading frames

NMD is one of the better characterized quality control mechanisms which acts as an mRNA surveillance pathway by degrading transcripts harboring premature translation termination codons (PTCs). However, several studies have also implicated NMD in the regulation of steady-state levels of physiological...

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Bibliographic Details
Main Author: Romão, Luísa (author)
Other Authors: Peixeiro, Isabel (author), Onofre, Claudia (author), Barbosa, Cristina (author), Teixeira, Alexandre (author)
Format: conferenceObject
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10400.18/2709
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/2709