The interplay between mRNA translation and nonsense-mediated decay in transcripts with short open reading frames

NMD is one of the better characterized quality control mechanisms which acts as an mRNA surveillance pathway by degrading transcripts harboring premature translation termination codons (PTCs). However, several studies have also implicated NMD in the regulation of steady-state levels of physiological...

ver descrição completa

Detalhes bibliográficos
Autor principal: Romão, Luísa (author)
Outros Autores: Peixeiro, Isabel (author), Onofre, Claudia (author), Barbosa, Cristina (author), Teixeira, Alexandre (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2015
Assuntos:
Doenças Genéticas
RNA
mRNA
Translational Regulation
Texto completo:http://hdl.handle.net/10400.18/2709
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/2709

Texto Completo

http://hdl.handle.net/10400.18/2709

Registos relacionados