Chitosan/sulfated locust bean gum nanoparticles: In vitro and in vivo evaluation towards an application in oral immunization

This work proposes the design of nanoparticles based on locus bean gum (LBG) and chitosan to be used as oral immunoadjuvant for vaccination purposes. LBG-based nanoparticles were prepared by mild polyelectrolyte complexation between chitosan (CS) and a synthesized LBG sulfate derivative (LBGS). Morp...

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Detalhes bibliográficos
Autor principal: Braz, L. (author)
Outros Autores: Grenha, Ana (author), Ferreira, Domingos (author), Rosa Da Costa, Ana (author), Gamazo, Carlos (author), Sarmento, Bruno (author)
Formato: article
Idioma:eng
Publicado em: 2019
Assuntos:
Polyelectrolyte complex nanoparticles
Loaded chitosan nanoparticles
Vaccine delivery
Immune-response
Salmonella-enteritidis
Hepatitis-B
Chitosan/Carrageenan nanoparticles
Immunoadjuvant properties
Bioadhesive capacity
Protein delivery
Texto completo:http://hdl.handle.net/10400.1/13217
País:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/13217

Texto Completo

http://hdl.handle.net/10400.1/13217

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