Inhibition of skeletal muscle S1-myosin ATPase by peroxynitrite

Exposure of myosin subfragment 1 (S1) to 3-morpholinosydnonimine (SIN-1) produced a time-dependent inhibition of the F-actin-stimulated S1 Mg2+-ATPase activity, reaching 50% inhibition with 46.7 ( 8.3 íM SIN-1 for 8.7 íM S1, that is, at a SIN-1/S1 molar ratio of approximately 5.5. The inhibition was...

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Detalhes bibliográficos
Autor principal: Tiago, Teresa (author)
Outros Autores: S, Simão (author), Aureliano, M. (author), Martín-Romero, Francisco Javier (author), Gutiérrez-Merino, Carlos (author)
Formato: article
Idioma:eng
Publicado em: 2012
Assuntos:
Texto completo:http://hdl.handle.net/10400.1/1355
País:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/1355