Tauroursodeoxycholic acid prevents E22Q Alzheimer's A beta toxicity in human cerebral endothelial cells

The vasculotropic E22Q mutant of the amyloid-beta (A beta) peptide is associated with hereditary cerebral hemorrhage with amyloidosis Dutch type. The cellular mechanism(s) of toxicity and nature of the A beta E22Q toxic assemblies are not completely understood. Comparative assessment of structural p...

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Bibliographic Details
Main Author: Viana, R. J. S. (author)
Other Authors: Nunes, A. F. (author), Castro, R. E. (author), Ramalho, R. M. (author), Meyerson, J. (author), Fossati, S. (author), Ghiso, J. (author), Rostagno, A. (author), Rodrigues, C. M. P. (author)
Format: article
Language:eng
Published: 2015
Subjects:
Biochemistry & Molecular Biology
Cell Biology
Online Access:http://hdl.handle.net/10451/21100
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21100

Internet

http://hdl.handle.net/10451/21100

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