Modeling Rett Syndrome With Human Patient-Specific Forebrain Organoids

Engineering brain organoids from human induced pluripotent stem cells (hiPSCs) is a powerful tool for modeling brain development and neurological disorders. Rett syndrome (RTT), a rare neurodevelopmental disorder, can greatly benefit from this technology, since it affects multiple neuronal subtypes...

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Bibliographic Details
Main Author: Gomes, AR (author)
Other Authors: Fernandes, TG (author), Vaz, SH (author), Silva, TP (author), Bekman, EP (author), Xapelli, S (author), Duarte, S (author), Ghazvini, M (author), Gribnau, J (author), Muotri, AR (author), Trujillo, CA (author), Sebastião, AM (author), Cabral, JM (author), Diogo, MM (author)
Format: article
Language:eng
Published: 2021
Subjects:
Rett syndrome
Disease modeling
Human induced pluripotent stem cells
Neurodevelopmental disorders
HDE NEU PED
Online Access:http://hdl.handle.net/10400.17/3722
Country:Portugal
Oai:oai:repositorio.chlc.min-saude.pt:10400.17/3722

Internet

http://hdl.handle.net/10400.17/3722

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