Genetic Variants of the MGAT5 Gene Are Functionally Implicated in the Modulation of T Cells Glycosylation and Plasma IgG Glycome Composition in Ulcerative Colitis

Objectives: The impact of genetic variants (single nucleotide polymorphisms [SNPs]) in the clinical heterogeneity of ulcerative colitis (UC) remains unclear. We showed that patients with UC exhibit a deficiency in MGAT5 glycogene transcription in intestinal T cells associated with a hyperimmune resp...

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Bibliographic Details
Main Author: Pereira, Márcia S. (author)
Other Authors: Durães, Cecília (author), Catarino, Telmo A. (author), Costa, José L. (author), Cleynen, Isabelle (author), Novokmet, Mislav (author), Krištić, Jasminka (author), Štambuk, Jerko (author), Conceição-Neto, Nádia (author), Machado, José C. (author), Marcos-Pinto, Ricardo (author), Magro, Fernando (author), Vermeire, Séverine (author), Lauc, Gordan (author), Lago, Paula (author), Pinho, Salomé S. (author)
Format: article
Language:eng
Published: 2021
Online Access:http://hdl.handle.net/10400.16/2565
Country:Portugal
Oai:oai:repositorio.chporto.pt:10400.16/2565

Internet

http://hdl.handle.net/10400.16/2565

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