Imidazolidin-4-one derivatives of primaquine as novel transmission-blocking antimalarials

Imidazolidin-4-one derivatives of primaquine were synthesized as potential double prodrugs of the parent drug. The title compounds inhibit the development of the sporogonic cycle of Plasmodium berghei, affecting the appearance of oocysts in the midguts of the mosquitoes. The imidazolidin-4-ones are...

ver descrição completa

Detalhes bibliográficos
Autor principal: Araujo, MJ (author)
Outros Autores: Bom, J (author), Capela, R (author), Casimiro, C (author), Chambel, P (author), Gomes, P (author), Iley, J (author), Lopes, F (author), Morais, J (author), Moreira, R (author), de Oliveira, E (author), do Rosario, V (author), Vale, N (author)
Formato: article
Idioma:eng
Publicado em: 2015
Assuntos:
Chemistry, Medicinal
Texto completo:http://hdl.handle.net/10451/21195
País:Portugal
Oai:oai:repositorio.ul.pt:10451/21195

Texto Completo

http://hdl.handle.net/10451/21195

Registos relacionados