Insights into (S)-rivastigmine inhibition of butyrylcholinesterase (BuChE): Molecular docking and saturation transfer difference NMR (STD-NMR)

Rivastigmine is a very important drug prescribed for the treatment of Alzheimer's disease (AD) symptoms. It is a dual inhibitor, in that it inhibits both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). For our screening program on the discovery of new rivastigmine analogue hits f...

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Detalhes bibliográficos
Autor principal: Bacalhau, P (author)
Outros Autores: Caldeira, Teresa (author), Martins, Rosário (author), Burke, Anthony (author)
Formato: article
Idioma:por
Publicado em: 2017
Assuntos:
Texto completo:http://hdl.handle.net/10174/19819
País:Portugal
Oai:oai:dspace.uevora.pt:10174/19819