Interplay between mutations and efflux in drug resistant clinical isolates of mycobacterium tuberculosis

Numerous studies show efflux as a universal bacterial mechanism contributing to antibiotic resistance and also that the activity of the antibiotics subject to efflux can be enhanced by the combined use of efflux inhibitors. Nevertheless, the contribution of efflux to the overall drug resistance leve...

Full description

Bibliographic Details
Main Author: Machado, Diana (author)
Other Authors: Coelho, Tatiane S (author), Perdigão, João (author), Pereira, Catarina (author), Couto, Isabel (author), Portugal, Isabel (author), Maschmann, Raquel De Abreu (author), Ramos, Daniela F (author), von Groll, Andrea (author), Rossetti, Maria L R (author), Silva, Pedro A (author), Viveiros, Miguel (author)
Format: article
Language:eng
Published: 2018
Subjects:
Efflux inhibitors
Synergism
TB eXIST
Time to detection
Tuberculosis
Infectious Diseases
Microbiology
Molecular Biology
SDG 3 - Good Health and Well-being
Online Access:http://hdl.handle.net/10362/36684
Country:Portugal
Oai:oai:run.unl.pt:10362/36684

Internet

http://hdl.handle.net/10362/36684

Similar Items