The interaction between mRNA translation and nonsense-mediated decay in AUG-proximal nonsense-mutated transcripts

Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that recognizes and rapidly degrades mRNAs containing premature termination codons (PTCs). Although NMD has been intensively studied, it is still poorly understood how NMD discriminates between PTCs and normal stop codons. The unified mode...

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Detalhes bibliográficos
Autor principal: Onofre, Cláudia (author)
Outros Autores: Menezes, Juliane (author), Peixeiro, Isabel (author), Romão, Luísa (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2025
Assuntos:
Genómica Funcional e Estrutural
Expressão Génica
Degradação do mRNA
Síntese Proteica
Nonsense-mediated mRNA Decay
Texto completo:http://hdl.handle.net/10400.18/4475
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/4475

Texto Completo

http://hdl.handle.net/10400.18/4475

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