The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs

Background: The emergence of resistance to anti-tuberculosis drugs is a serious and growing threat to public health. Next-generation sequencing is rapidly gaining traction as a diagnostic tool for investigating drug resistance in Mycobacterium tuberculosis to aid treatment decisions. However, there...

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Detalhes bibliográficos
Autor principal: Phelan, Jody (author)
Outros Autores: O'Sullivan, Denise M. (author), Machado, Diana (author), Ramos, Jorge (author), Whale, Alexandra S. (author), O'Grady, Justin (author), Dheda, Keertan (author), Campino, Susana (author), McNerney, Ruth (author), Viveiros, Miguel (author), Huggett, Jim F. (author), Clark, Taane G. (author)
Formato: article
Idioma:eng
Publicado em: 2018
Assuntos:
Diagnostics
Drug resistance
Drug-susceptibility testing
Next-generation sequencing
Tuberculosis
XDR-TB
Molecular Medicine
Molecular Biology
Genetics
Genetics(clinical)
Infectious Diseases
SDG 3 - Good Health and Well-being
Texto completo:https://doi.org/10.1186/s13073-016-0385-x
País:Portugal
Oai:oai:run.unl.pt:10362/36610

Texto Completo

https://doi.org/10.1186/s13073-016-0385-x

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