Amplified and Homozygously Deleted Genes in Glioblastoma: Impact on Gene Expression Levels

BACKGROUND: Glioblastoma multiforme (GBM) displays multiple amplicons and homozygous deletions that involve relevant pathogenic genes and other genes whose role remains unknown. METHODOLOGY: Single-nucleotide polymorphism (SNP)-arrays were used to determine the frequency of recurrent amplicons and h...

ver descrição completa

Detalhes bibliográficos
Autor principal: Crespo, I (author)
Outros Autores: Tão, H (author), Nieto, AB (author), Rebelo, O (author), Domingos, P (author), Vital, AL (author), Patino, MC (author), Barbosa, MD (author), Lopes, MC (author), Resende de Oliveira, C (author), Orfão, A (author), Tabernero, MD (author)
Formato: article
Idioma:eng
Publicado em: 2013
Assuntos:
Glioblastoma
Homozigoto
Delecção do Gene
Regulação Neoplásica da Expressão Génica
Texto completo:http://hdl.handle.net/10400.4/1528
País:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/1528

Texto Completo

http://hdl.handle.net/10400.4/1528

Registros relacionados