An easy-to-use liquid chromatography assay for the analysis of lamotrigine in rat plasma and brain samples using microextraction by packed sorbent:Application to a pharmacokinetic study

A simple and rapid high-performance liquid chromatography method with diode-array detection (HPLC-DAD) using microextraction by packed sorbent (MEPS) during the sample preparation step was developed and validated to quantify lamotrigine (LTG) in rat plasma and brain samples. MEPS variables such as p...

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Bibliographic Details
Main Author: Ventura, Sandra (author)
Other Authors: Rodrigues, Márcio (author), Pousinho, Sarah (author), Falcão, Amílcar (author), Alves, Gilberto (author)
Format: article
Language:eng
Published: 2016
Subjects:
Bioanalytical method validation
High-performance liquid chromatography
Lamotrigine
Microextraction by packed sorbent
Rat plasma and brain
Online Access:http://hdl.handle.net/10314/3099
Country:Portugal
Oai:oai:bdigital.ipg.pt:10314/3099

Internet

http://hdl.handle.net/10314/3099

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